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This experiment was performed in order to study the effects of haepyoyijintang on the injured tracheal tissue induced SO$_{2}$ in rats. Healthy adult male rats weighting about 250g were divided into 4 groups-the Normal group, the Control group, the group of Haepyoyijintang administration for 5days after SO$_{2}$gas exposure (Sample Ⅰ), and the group of Haepyoyijintang adiministration for 10 days before and for 5days after SO$_{2}$ gas exposure (Sample Ⅱ). The results were obtained as follows; 1. In the trachea Control group, the lesion of the ciliated epithelium was and the mucus secretion of the respiratory tract was increased iginificantly. 2. In the trachea of SampleⅠgroup, the lesion of the ciliated epithelium and the mucus secretion of the respiratory tract were decreased compared with Control group. 3. In the trachea of SampleⅡgroup, the lesion of the ciliated epithelium and the mucus secretion of the respiratory tract were decreased compared with Control and Sample Ⅰgroup. According to the above results, Haepyoyijintang has significant effects on the injuried tracheal tissu caused by SO$_{2}$ in rats.
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